Studying the impact of the low-frequency atmospheric oscillations such as the Quasi-Biennial Oscillation (QBO) on the Mediterranean storm track can prove important in increasing accuracy of medium-range weather forecasting and predication in monthly and seasonal time scales. In this study, using the NCEP/NCAR reanalysis data with the grid spacing of 2.5 degrees in both zonal and meridional directions during the period 1958 to 2018, the wave activity density and flux, as well as the divergence of wave activity flux are computed for two periods of early winter (November–December) and late winter (January–February–March). The results showed that the Mediterranean storm track is stronger and displaces to the east in the westerly phase of QBO in early winter. In the late winter, however, it is in the easterly phase of QBO that the Mediterranean storm track becomes stronger and displaced to the east.