Geophysical airborne and satellite data are of great importance today in large-scale and regional studies and most of the big exploration projects are performed using this data around the world. Due to the low cost, extensive coverage and high speed of field operations, the airborne magnetometry is of great interest to various institutions and organizations today. This study investigates the changes trend in the Zagros zone using airborne magnetic data. Then, upper magnetic anomaly depth estimation was performed by applying Euler deconvolution depth estimation method. This depth shows the thickness of the non-magnetic sediments. According to the results obtained in the Zagros zone, the thickness of the sediments varies from 2, 3 to 15 km. The general trend of these changes increases from the Uromieh-Dokhtar Zone to the Zagros Tectonic Zone. The amplitude of the magnetic field changes follows the same trend. In the studied area, the Urmia-Dokhtar volcanic zone has the strongest magnetic responses and this trend decreases toward the Zagros tectonic zone.